盐酸胍(医药级)

盐酸胍(医药级)一、产品基本信息中文名:盐酸胍外文名:Guanidine Hydrochloride别    名:氨基甲脒盐酸盐化学式:CH6ClN3分子量:95.53CAS号:50-01-1外    观:白色结晶颗粒应用领域:1、医药中间体合成磺胺类药物（如磺胺嘧啶、磺胺甲基嘧啶）的关键原料159；用于生产抗贫血药叶酸及抗病毒药物中间体。2、生物技术领域蛋白质变性剂：破坏细胞膜结构，使核蛋白与核酸分离，用于RNA提取（如灭活RNase）；蛋白质复性剂：溶解包涵体并辅助蛋白质折叠恢复活性（常与尿素、DTT联用）；病毒灭活：高浓度下可灭活HSV-1、柯萨奇病毒等。3、工业与其他应用合成纤维防静电剂、油田杀菌阻垢剂；石墨烯制备中的还原剂。表：主要应用领域及作用机制领域 作用机制 具体应用案例制药 嘧啶环合成原料 磺胺嘧啶、叶酸生产核酸提取 变性蛋白质，抑制RNase 细胞总RNA提取蛋白质工程 溶解变性蛋白，辅助复性 包涵体处理、酶活性恢复工业防腐 广谱杀菌 油田回注水杀菌阻垢质量标准项目名称技术指标外观　白色晶体含量 ≥99.5铵盐 ≤0.03水不溶物 ≤0.02水分 ≤0.3灰分 ≤0.02水溶性试验澄清无色熔点范围℃183-188吸光度 （紫外线波长260nm） A(260nm)≤0.04吸光度 （紫外线波长280nm）A(280nm)≤0.02PH值(4%水溶液)6.4±0.2包装：25千克纸板桶。Guanidine hydrochloride for MedicineGuanidine hydrochloride for Medicine is used for A strong denaturant was extracted from cells for denaturation and renaturation of protein.Downstream processing in biopharmaceutical manufacturingDiagnostics (extraction buffers for the isolation of nucleic acids from biological specimens, test kits for viral RNA/DNA in clinical diagnostics)Mbth: guanidinine hydrochloride Alias: amidoformamidine hydrochloride Chemical formula: CH6ClN3 Molecular weight: 95.53 CAS NO.: 50-01-1 EINECS NO.: 200-002-3 Melting point: 181℃ Water solubility: 1.354 g/cm3Appearance: white crystal particles should beHazard symbol: description of hazardous hazard: R22 R36/38.Usage:Guanidine hydrochloride is produced by dicyandiamide and ammonia chloride as the main raw materials, used as pharmaceutical intermediates of organic synthesis, and is the important raw material to manufacture sulfa drugs, folic acid. sulfadiazine, sulfanilamide methyl pyridine. sulfanilamide dimethyl pyrimidine. In addition, it is used as a strong denaturant in the RNA cell extraction experiments. The Guanidine hydrochloride solution can dissolve protein, which leads to the destruction of the cellular structure and the nucleoprotein secondary structure; departing from the nucleic acid, the RNA enzymes can be inactivated by guanidine hydrochloride and other reducing agents. The industrial-grade guanidine hydrochloride and 60% guanidine hydrochloride solution are the intermediates in making the pesticides, dyes and organic synthesis. They also can be used as antistatic agent of the synthetic fiber.SpecificationPharmaceutic gradeAppearancewhite crystalline powderContent ≥%99.5Content of Ammonium Chloride ≤%0.05Insoluble matter in water≤%0.02Moisture≤%0.3Ash conten≤%0.02Water SolubilityClear and ColorlessMelting poin℃183-188UV Absorption 260μm≤0.04UV Absorption 280μm≤0.02PH Coten(4% Aqueous Solution)6.4±0.2Proportion d4200.02Packing: 25 kg cardboard barrel with plastic bag inside.

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